Exploring the Efficacy of Homeopathic Medicine in the Treatment of Eating Disorders: A Comprehensive Review

 Exploring the Efficacy of Homeopathic Medicine in the Treatment of Eating Disorders: A Comprehensive Review

Abstract-

Eating disorders can profoundly affect the individual and family unit. Changes in the individual include disturbances in body perception, organ damage, and increased risk factors leading to ill health in later years. There is thus a fundamental requirement to adequately diagnose, treat, and manage those individuals with eating disorders which the American Psychiatric Association has recently categorized (DSM-5) into Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, and Other Specified- and Unspecified-Feeding or eating disorders. This reference work aims to describe, in one comprehensive resource, the complex relationships between eating disorders, diet, and nutrition. In this regard, eating disorders are psychiatric conditions though some eating disorders have a genetic basis. Genetic influences will also include polymorphisms. It will provide a framework to unravel the complex links between eating disorders and health-related outcomes and provide practical and useful information for diagnosis and treatment. The volume will also address macronutrients, micronutrients, pharmacology, psychology, genetics, tissue and organ damage, appetite, and biochemistry, as well as the effect of eating disorders on family and community. The material will enhance the knowledge base of dietitians, nutritionists, psychiatrists and behavioral scientists, health care workers, physicians, educationalists, and all those involved in diagnosing and treating eating disorders. Homeopathy, a holistic system of medicine based on the principle of "like cures like" and individualized treatment, has emerged as a potential adjunctive therapy for eating disorders. This abstract provides a comprehensive review of the existing literature on the efficacy of homeopathic medicine in the treatment of eating disorders. Through a systematic examination of peer-reviewed studies, clinical trials, and case reports, this review aims to evaluate the evidence supporting the use of homeopathic remedies in managing the symptoms and promoting the holistic well-being of individuals with eating disorders. While preliminary findings suggest potential benefits of homeopathic treatment, including improvements in emotional stability, self-esteem, and overall quality of life, further research is to establish its efficacy conclusively. The abstract concludes by highlighting the need for rigorous scientific inquiry and collaborative efforts between conventional and complementary healthcare providers to optimize treatment outcomes for individuals with eating disorders.

Keywords: Eating disorders, anorexia nervosa, bulimia nervosa, binge eating disorder, pathophysiology, Homoeopathy

 Introduction

A. BACKGROUND ON EATING DISORDERS: The earliest historical descriptions of people experiencing symptoms consistent with modern-day eating disorders date back to Hellenistic (323 BC-31 BC) and medieval times (fifth -15th century AD). Around this time, purification through the denial of physical needs and the material world emerged as a cultural theme. There is a report of an upper-class twenty-year-old Roman girl starving herself to death in pursuit of holiness. There are additional accounts from the Middle Ages of extreme self-induced fasting that often led to premature death by starvation— Catherina of Siena is one example. Deprivation of food was seen as a spiritual practice and women were disproportionately afflicted. Some contemporary authors have dubbed these fasting habits “holy anorexia.” In 1689, English physician Richard Morton described two cases of “nervous consumption” —one in a boy and one in a girl. These are considered the earliest modern cases of the illness we now know as anorexia nervosa. He described the lack of a physical explanation for the loss of appetite and wasting and hence, determined “this Consumption to be Nervous. “The next cases reported were about 200 years later. In 1873, Sir William Gull, another English physician, coined the term “anorexia nervosa” in published case reports. Also, in 1873, a French physician, Ernest Charles LA Segue published descriptions of individuals with “anorexia hysteric.

B. INTRODUCTION TO HOMOEOPATHY AND ITS PRINCIPLES: Homoeopathy, founded by Dr. Hahnemann, uses potentized remedies to stimulate the body's innate healing abilities. It follows the Law of Similar, treating diseases with substances that. Homeopathic treatment for eating disorders: a comprehensive overview and promising therapeutic approach International Journal of Science and Healthcare Research (www.ijshr.com) 228 Volume 8; Issue: 3; July-September 2023 produces similar symptoms in healthy individuals. The unique and comprehensive remedy that covers an individual's symptoms is called the "Homoeopathic simillimum," achieved through potentization/dynamization, a process involving dilution and succussion. This comprehensive approach aims to promote natural healing. An eating disorder is a serious, complex, mental health issue that one’s affects emotional and physical health. People with eating disorders develop an unhealthy relationship with food, their weight, or their appearance. Anorexia, bulimia, and binge eating disorder are all types of eating disorders. Eating disorders are treatable.

OVERVIEW OF EATING DISORDERS:

DEFINITION: An eating disorder is a serious, complex, mental health issue that one’s affects emotional and physical health. People with eating disorders develop an unhealthy relationship with food, their weight, or appearance. Anorexia, bulimia, and binge eating disorder are all types of eating disorders. Eating disorders are treatable. People with untreated eating disorders may develop life-threatening problems. Approximately 20 million girls and women and 10 million boys and men in America have an eating disorder. Eating disorders are caused by several complex factors including genetics, brain biology, personality, cultural and social ideals, and mental health issues.

 

 

There are different types of eating disorders. Some people may have more than one type of eating disorder. Types include:

 

  • Anorexia nervosa: People with anorexia nervosa greatly restrict food and calories sometimes to the point of self-starvation. You can have anorexia at any body size. It is characterized by an obsessive desire to lose weight and a refusal to eat healthy amounts of food for your body type and activity level.
  • Bulimia nervosa: People diagnosed with bulimia nervosa binge or eat, or perceive they ate, large amounts of food over a short time. Afterward, they may force themselves to purge the calories in some way such as vomiting, using laxatives, or exercising excessively to rid their body of the food and calories.
  • Binge eating disorder (BED): People who have a binge eating disorder experience compulsory eating behaviors. They eat or perceive that they have eaten, large amounts of food in a short period. However, after binging they don’t purge food or burn off calories with exercise. Instead, they feel uncomfortably full and may struggle with shame, regret, guilt, or depression.

 

·        Eating disorders can develop at any age. They affect all genders, races, and ethnicities. It’s a myth that eating disorders mostly affect girls and women. Boys and men are equally at risk. Certain factors may make you more prone to developing an eating disorder, such as a family history of eating disorders, addiction, or other mental health issues, such as depression. A history of trauma (physical, emotional, or sexual). Personal history of anxiety, depression, or obsessive-compulsive disorder (OCD). History of dieting. Other factors include Diabetes (up to one-fourth of women with Type 1 diabetes develop an eating disorder). Involvement in activities that focus on a slender appearance, such as modeling, gymnastics, swimming, wrestling, and running. Major life changes, such as starting a new school or job, a divorce, or a move. Perfectionistic tendencies. A mix of genetics, environment, and social factors play a role in the development of eating disorders. Some people with eating disorders may use extreme measures to limit food intake or food groups when they feel like other aspects of their lives are hard to manage. An obsession with food becomes an unhealthy way of coping with painful emotions or feelings. Thus, eating disorders are more about finding healthy ways to manage your emotions than about food. Symptoms: Mood swings. Fatigue, fainting or dizziness. Thinning hair or hair loss. Frequent bathroom breaks after eating. Unexplained weight changes or drastic weight loss. Unusual sweating or hot flashes. Other changes could include Solo dining or not wanting to eat with other people. Withdrawing from friends or social activities. Hiding food or throwing it away. Fixation on food, calories, exercise, or weight loss

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Pathophysiology and Natural History

Biologic and psychosocial factors are implicated in the pathophysiology of eating disorders, but the underlying causes and mechanisms remain unknown.

Biologic Factors

First–degree female relatives and monozygotic twin offspring of patients with anorexia nervosa have higher rates of anorexia nervosa and bulimia nervosa. Children of patients with anorexia nervosa have a lifetime risk for anorexia nervosa that is tenfold that of the general population (5%). Families of patients with bulimia nervosa have higher rates of substance abuse, particularly alcoholism, affective disorders, and obesity.

Endogenous opioids might contribute to the denial of hunger in patients with anorexia nervosa. Some hypothesize that dieting can increase the risk of developing an eating disorder. Increased endorphin levels have been described in patients with bulimia nervosa after purging and may induce feelings of well-being. Diminished norepinephrine turnover and activity are suggested by reduced levels of 3–methoxy–4–hydroxyphenyl glycol in the urine and cerebrospinal fluid of some patients with anorexia nervosa. Antidepressants often benefit patients with bulimia nervosa and support a pathophysiologic role for serotonin and norepinephrine.

Starvation results in many biochemical changes such as hypercortisolemia, no suppression of dexamethasone, suppression of thyroid function, and amenorrhea. Several computed tomography studies of the brain have revealed enlarged sulci and ventricles, a finding that is reversed with weight gain. In one study using positron emission tomography, metabolism was higher in the caudate nucleus during the anorectic state than after hyperalimentation.

Anorexia risk may increase with a polymorphism of the promoter region of the serotonin 2a receptor. The melanocortin 4 receptor gene is hypothesized to regulate weight and appetite. Polymorphism in the gene for agouti-related peptide might also play a role at the melanocortin receptor. In bulimia nervosa, there is excessive secretion of ghrelin. Ghrelin receptor gene polymorphism is associated with both hyperphagia of bulimia and Prader–Willi syndrome.

Perhaps some of the most fascinating new research addresses the overlap between uncontrolled compulsive eating and compulsive drug seeking in drug addiction.19 Reduction in ventral striatal dopamine is found in both of these groups. A lower frequency of dopamine D2 receptors was associated with a higher body mass index. Obese persons might eat to temporarily increase activity in these reward circuits. Frequent visual food stimuli paired with increased sensitivity of right orbitofrontal brain activity are likely to initiate eating behavior. Marijuana’s well–known appetite stimulant effect is likely due to its agonist activity at cannabinoid receptors, and cannabinoid receptor antagonism has been associated with reduced binge eating.

Psychosocial Factors

High levels of hostility, chaos, and isolation and low levels of nurturance and empathy are reported in families of children presenting with eating disorders. Anorexia has been postulated as a reaction to demands on adolescents to behave more independently or to respond to societal pressures to be slender. Anorexia nervosa patients are usually high achievers, and two–thirds live at home with their parents. Many consider their bodies to be under the control of their parents. Young Asian female immigrants are at increased risk for anorexia or bulimia as compared with peers living in their homeland. First-generation daughters of Asian immigrants are at higher risk than U.S. females of the same age. Family dynamics alone, however, do not cause anorexia nervosa. Self-starvation may be an effort to gain validation as a unique person. Patients with bulimia nervosa have been described as having difficulties with impulse regulation.

Course and Prognosis

As a general guideline, it appears that a third of patients fully recover, a third retain subthreshold symptoms, and a third maintain a chronic eating disorder.

Anorexia Nervosa

Long–term follow-up shows recovery rates ranging from 44% to 76%, with prolonged recovery time (57 to 59 months). Mortality (up to 20%) is primarily from cardiac arrest or suicide good prognostic factors are an admission of hunger, lessening of denial, and improved self–esteem. Poorer prognostic factors are initial lower minimum weight, presence of vomiting or laxative abuse, failure to respond to previous treatment, disturbed family relationships, and conflicts with parents.

Bulimia Nervosa

Little long–term follow-up data exist. Short–term success is 50% to 70%, with relapse rates between 30% and 50% after 6 months. These patients have an overall better prognosis as compared with anorexia nervosa patients. Poor prognostic factors are hospitalization, higher frequency of vomiting, poor social and occupational functioning, poor motivation for recovery, severity of purging, presence of medical complications, high levels of impulsivity, longer duration of illness, delayed treatment, and premorbid history of obesity and substance abuse.

Pica

Recently included in the DSM–5, pica is described as the eating of non-food substances for at least 1 month. The symptoms should be severe enough that warrant clinical attention. Some of the substances that patients ingested tend to vary according to age and environmental availability such as paper, hair, wool, starch, ice, charcoal, and pebbles, among others. Normally, these patients are not complaining about food aversion. Some biological abnormalities such as vitamin deficiencies or mineral deficiencies have been reported frequently in these patients. Also, patients with certain medical conditions such as infections, intestinal obstruction, and mechanical bowel problems are more likely to suffer from this condition. The prevalence is unclear; in patients with developmental disability, the prevalence appears to increase with the severity of the disability. Even though pica is more frequently reported in children, it can occur at any age.

Rumination Disorder

The prevalence of rumination disorders is unknown but is certainly higher in patients with developmental disabilities. Patients under stressful situations such as neglect, stressful life, and problems in the relationship with the parents are certainly more frequent in infants and young children.

 

 

 

 Complication-eating disorders are the second most lethal psychiatric disorder, followed only by opioid use disorder. Greatly restricting calories, throwing up or extreme exercise can take a toll on your overall health. An untreated eating disorder places you at risk for serious problems, such as Arrhythmia, heart failure, and other heart problems. Acid reflux (gastroesophageal reflux disease or GERD). Gastrointestinal problems. Low blood pressure (hypotension). Organ failure and brain damage. Osteoporosis and tooth damage. Severe dehydration and constipation. Stopped menstrual cycles (amenorrhea) and infertility. Stroke.

 Management: Psychotherapy: A mental health professional can determine the best psychotherapy for your situation. Many people with eating disorders improve with cognitive behavioral therapy (CBT). This form of therapy helps you understand and change distorted thinking patterns that drive behaviors and emotions.

Maudsley approach: This form of family therapy helps parents of teenagers with anorexia. Parents actively guide a child’s eating while they learn healthier habits.

Medications: Some people with eating disorders have other conditions, like anxiety or depression. Taking antidepressants or other medications can improve these conditions. As a result, your thoughts about yourself and food improve.

Nutrition counseling: A registered dietitian with training in eating disorders can help improve eating habits and develop nutritious meal plans. This specialist can also offer tips for grocery shopping, meal planning, and preparation.

The best treatment approach is often a combination of all of these professionals working together to obtain a comprehensive treatment to address the physical, mental, and behavioral aspects.

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HOMOEOPATHIC APPROACH TO EATING DISORDERS

In homeopathic treatment for eating disorders, potentized remedies are utilized to stimulate the body's natural healing capabilities. Homeopathy views everyone as unique, considering their physical, mental, and emotional symptoms to prescribe individualized remedies. While there is no specific miasm associated solely with eating disorders, it is believed that certain miasms can play a role in their manifestation. Psora is considered the foundational miasm and is associated with a fundamental susceptibility and imbalance in the vital force. It can contribute to disturbances in the body's metabolism, including issues with digestion and assimilation. This miasm may be linked to symptoms of malnourishment, weak vitality, and an underlying sense of lack or insufficiency. From a miasmatic standpoint, here are some general aspects of the sycosis miasm that could be connected to eating disorders: Suppression of emotions, Obsessive-compulsive tendencies, Control issues, and Body image concerns: Another miasm that could be involved in eating disorders is the Syphilitic miasm. Syphilis miasm represents a deeper, destructive energy and can manifest as self-destructive tendencies, obsessive behaviors, and distorted body image. This miasm may be related to the extreme measures and harmful practices individuals with eating Dr such as severe dietary restrictions, purging, or excessive exercise.

ANOREXIA NERVOSA: IGNATIAAMARA: • Vomiting of everything taken into stomach • Eats gentle food, a little toast, and the simplest possible things because she has been vomiting for days. • Hysterical stomach • She is a worn-out, nervous person. • A continuous state of fright or apprehensive state that something is going to happen

NATRUM MURIATICUM: • Anaemic, cachectic with great emaciation. • Loses flesh while living well. • Emaciation marked in neck and throat. • Aversion to bread • Craves salt. • Sweats while eating. • Aversion to fatty food, rich and bread • Sickly looking skin yellow, often chlorotic skin • Skin looks dry, withered, shrunken, • dropsical • Emaciation takes place from above downwards. • Collar bone becomes prominent. • Food digestion takes an extraordinarily long period. • All the symptoms are aggravated by eating. • Whitish slimy mucous is vomited with relief. • Menses irregular suppressed menses.[17] • The menses, which had been suppressed for eighty-five days, come back, followed soon after by great heaviness in the lower limbs.

FERRUM METALLICUM: Sudden emaciation with false plethora Bones are soft. Vomiting of food immediately after midnight. Loss of appetite. After eating, discomfort, and heaviness in the stomach.

 GENTIANA LUTEA: • Anorexia • Bitter taste in mouth. • Inclination to vomit • Vomiting in weak subjects • Ravenous hunger in the evening. • Nausea after simplest meals. • Continual emission of wind above and below without relief.

ABROTANUM: Appetite good but emaciation progresses. Food passes undigested.  Gnawing hunger and whining, Emaciation starts in the lower extremities and move up the body gradually, affecting the face last.  The person is very weak and unable to hold up their head.  Irritable person

BULIMIA NERVOSA: CINA  Ravenous hunger; sinking immediately after a meal.  Hunger comes in the middle of the night; feel hungry a few min after a meal.  Vomiting / Diarrhoea immediately after eating and drinking.  after vomiting you would expect this would be an aversion to food, but there is the same empty hungry feeling.

 ALFALFA Generally, appetite is impaired, but in the case of bulimia, the appetite is increased.  Increased thirst. Must consume food regularly since he cannot wait for scheduled meals. Early in the day hunger, Craving for sweets.

URANIUM NITRICUM -Indicated in case of bulimia nervosa.  Ravenous appetite, eating followed by flatulence.  Bloating in the abdomen.  Great emaciation and profound debility.

ZINCUM METALLICUM - Nausea and vomiting of bitter mucous.  Ravenous hunger at about 11 am.  Extreme gluttony when eating; cannot eat quickly enough. Marked anemia with profound prostration.

BINGE EATING DISORDER: ABIES CANADENSIS:  Great appetite, tendency to Overeat, gnawing, hungry, faint feeling in epigastric. Craves meat, pickles, and other coarse food.

A propensity to consume a lot more than your stomach can handle.  Canine hunger

ANACARDIUM- Sensation of emptiness in the stomach; eating briefly eases all pain. Swallow food & drinks hastily  Eructation; Nausea &vomiting.  After a meal; hypochondriacal humor; pressure & tension in the precordial region; stomach &belly  Great fatigue & Desire to sleep. Great fatigue; extreme weakness in limbs.

ANTIMONIUM CRUDUM:  For children and young people inclined to grow fat. Gastric complaints from overeating. Digestion disturbed. Agg after eating. Bloating after eating  Constant belching. Corresponds to race of swine.  Abnormal hunger; is not relieved by eating. Emptiness at epigastrium. A strong urge to eat food that is not appropriate for one's level of fitness. Loathing of food; inclination to vomit. Nausea and vomiting from overloading of the stomach.  Emaciation/ great obesity. Sudden attacks of the weakness of fainting. Stomach distended; vomits the contents of stomach prolonged retching; nausea.

Reference-REFERENCES 1. Mulheim L. History of eating disorders. Very well mind. March 23, 2020. Available from: https://www.verywellmind.com/history-ofeating-disorders-4768486

2. Razlog R, Pellow J, Patel R, Caminsky M. Case study on the homeopathic treatment of binge eating in adult males. Science Direct. December 2016. Available from: https://www.sciencedirect.com/science/articl e/pii/S1025984816300205

3. ANAD. Eating Disorder Statistics | General & Diversity Stats | ANAD [Internet]. National Association of Anorexia Nervosa and Associated Disorders. ANAD; 2021. Available from: https://anad.org/eatingdisorders-statistics/ 4. World Health Organization. ICD-11 for Mortality and Morbidity Statistics. Geneva: World Health Organization; 2018.

5. Harrison P, Cowen P, Burns T, Fazel M. Shorter Oxford Textbook of Psychiatry. 7th ed. Oxford University Press; pg. 313-317, 321.

6. Bulik CM, Thornton LM, Root TL, et al. Understanding the genetic risk architecture and underlying biological mechanisms of eating disorders. Am J Psychiatry. 2016;173(8):737-748. 7. Watson HJ, Bulik CM. Update on the treatment of anorexia nervosa: Review of clinical trials, practice guidelines, and emerging interventions. Psychol Med. 2018; 48(8):1228-1256.

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